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Not getting pregnant, despite having carefully timed, unprotected sex for one year. The cause of infertility may be difficult to determine but may include inadequate levels of certain hormones in both men and women, and trouble with ovulation in women. The main symptom is an inability to get pregnant. In many cases, there are no additional symptoms. Many treatments significantly improve the chances of getting pregnant. They include hormone treatments, fertility drugs and surgery. In addition, assisted reproduction uses various medical techniques to fertilise an egg.